Middle Musquodoboit is a rural community in the Musquodoboit Valley region of Nova Scotia, Canada, situated within the Halifax Regional Municipality. It lies along the Musquodoboit River at the junction of Route 357 and Route 224, approximately 78 kilometres from Dartmouth, Nova Scotia. The community’s name derives from the First Nations word Mooskoduboogwek, meaning to suddenly widen out after a narrow entrance at a mouth.
For a period following 1883, Middle Musquodoboit was known as Laytonville, though it eventually reverted to its original name.